Stephanie Greene, MD

Associate Professor
Director, Vascular Neurosurgery, Children's Hospital of Pittsburgh
Director, Perinatal Neurosurgery, Children's Hospital of Pittsburgh

Stephanie Greene




Stephanie Greene, MD, joined the faculty of the Department of Neurological Surgery in the pediatric neurosurgery division at Children’s Hospital of Pittsburgh in 2009.

Dr. Greene graduated from Dartmouth College in 1993 with a degree in biology and psychology, and a concentration in neuroscience. She earned her medical degree from Albany Medical College, and completed her neurosurgical residency at Harvard University in the Brigham & Women’s and Children’s Hospital of Boston program.

Her fellowship in pediatric neurosurgery was completed through the University of Washington program at Seattle Children’s Hospital in 2005. She is board certified in adult and pediatric neurosurgery. She was the director of pediatric neurosurgery at Hasbro Children’s Hospital, affiliated with Brown University, prior to accepting her position at Children’s Hospital of Pittsburgh. She is the director of vascular neurosurgery and perinatal neurosurgery at Children’s Hospital of Pittsburgh.

Specialized Areas of Interest

Vascular malformations; MoyaMoya syndrome; Chiari malformation; spinal dysraphism; peripheral nerve disorders; brain tumors; fetal surgery.

Board Certifications

American Board of Neurological Surgeons
American Board of Pediatric Neurological Surgeons

Hospital Privileges

Children’s Hospital of Pittsburgh of UPMC
Magee-Womens Hospital of UPMC

Professional Organization Membership

American Association of Neurological Surgeons
American Society of Pediatric Neurosurgeons
AANS/CNS Joint Section on Pediatric Neurosurgery
AANS/CNS Joint Section on Tumors
Congress of Neurological Surgeons
Pediatric Craniocervical Society
Pennsylvania Neurosurgical Society
Sigma Xi
Women in Neurosurgery
World Federation of Neurosurgical Societies

Education & Training

AB, Biology/Psychology, Dartmouth College, 1993
MD, Albany Medical College, 1998
Residency, Neurosurgery, Penn State University, 2000
Residency, Neurosurgery, Harvard University, 2004
Fellowship, Pediatric Neurosurgery, 2005

Honors & Awards

Castle Connolly Exceptional Women in Medicine, 2017
American’s Most Honored Professionals (American Registry), 2017
Castle Connolly Regional Top Doctor, 2017
Castle Connolly Metro Area Top Doctor, 2016
Castle Connolly Top Doctor, 2016
Top Ten Doctor – Metro Area, City, and State (, 2013-present
Patients’ Choice 5-Year Honoree, 2013-present
America’s Most Compassionate Doctors, 2011-present
America’s Top Surgeons, 2007, 2011, 2012
Patients’ Choice Award, 2008- present

Selected Publications

Gandhoke GS, Yilmaz S, Grunwaldt L, Hamilton R, Salvetti DJ, Greene S. Spinal epidural venous malformation with mediastinal extension: case report and review of the literature. J Neurosurg Peds 1-6, 2016.

Kooshkabadi A, Jankowitz B, Choi PA, Weiner GM, Greene S. Thrombosis and spontaneous recanalization of a giant intracranial aneurysm: diagnosis and management pearls in a pediatric patient. J Neurosurg Peds 15(1):78-81, 2015. 

Pal R, Greene S. miRNA-10b promotes medulloblastoma proliferation and survival via Bcl2. PLOS One 10(9), 2015.

Tian AT, Foster KA, Jakacki R, Reyes-Mugica M, Greene S. Neurocutaneous melanosis is associated with tethered spinal cord. Childs Nervous System 31(1):115-21, 2015. 

Tormenti M, Lam S, Lin Y, Greene S. The putative relationship netween Chiari I malformation and obesity in teenagers. J Ped Neurosci 10(4):321-5, 2015.

Zwagerman NT, Foster KA, Jakacki R, Khan FH, Yock TI, Greene S. The development of moyamoya syndrome after proton beam therapy. Pediatr Blood and Cancer, 61:1490-92, 2014. 

Karandikar M, Yellon RF, Murdoch G, Greene S. Co-existence of dermal sinus tract, dermoid cyst, and encephalocele in a patient presenting with nasal cellulitis. J Neurosurg Peds 11:91-94, 2013.

Bonfield C, Lam S, Lin Y, Greene S. The impact of attention deficit-hyperactivity disorder on recovery from closed head injury. J Neurosurg Peds 12(2):97-102, 2013.

Zwagerman NT, Ricks C, Foster KA, Greene S. Symptomatic thoracic arachnoid cyst with coexisting tick paralysis: case report and review of the literature. Pediatric Neurosurgery 49(6):360-4, 2013.

11. Lam SK, Grandhi R, Wong R, Hamilton RG, Greene S. Neuromuscular hamartoma of the sciatic nerve: case report and review of the literature. Surgical Neurology 4(1):8- 11, 2013.

A complete list of Dr. Greene's publications can be reviewed through the National Library of Medicine's publication database.

Research Activities

Dr. Greene’s research studies feature Moyamoya studies including one identifying a noninvasive, radiation-free method of quantifying vascular reserve and a patient’s risk of stroke, both pre- and post-operatively. Another study seeks to standardize the anesthetic management of these patients to minimize their perioperative stroke risk. A third is investigating the relationship between the length of arterial indirect bypass and the degree of resultant neovascularization.

The outcomes of a large series of arteriovenous malformations treated at Children’s Hospital of Pittsburgh with a combination of gamma knife radiosurgery, endovascular embolization, and open surgery are being studied. The outcomes of myelomeningocele patients with regard to Chiari II malformation and tethered cord syndrome are being described in separate publications.

Media Appearances

Mt. Pleasant girl overcomes effects of brain surgery
March 5, 2014
Pittsburgh Tribune-Review

ADHD May Be Tied to Longer-Lasting Head Injury
June 25, 2013
U.S. News & World Report Health Day

UPMC Videos & Patient Stories

Surgical Treatment of Moyamoya in the Pediatric Population
Dr. Greene explains how surgical intervention is the only viable treatment to effectively halt neurological decline associated with moyamoya.

Brain Care Institute Patient Story: Nathan’s Story
See how one family found help for moyamoya through the expertise of Dr. Greene of the Brain Care Institute.