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Diet
and Lifestyle
There is no information to suggest that either diet or lifestyle is effective
in the treatment of patients with acoustic tumors. Nevertheless, patients
should maintain good nutritional status, particularly before any planned
resective surgery in order to assist wound healing.
Pharmacologic
Treatment
There is limited information regarding the role of chemotherapy or hormonal
therapy for patients. Drug therapy does not play a role in almost all
patients but could be considered for patients with tumors that recur despite
resection or irradiation. Such patients are very rare.
Assistive
Devices
The most important new assistive device for acoustic tumor patients is
the brainstem auditory implant. This device has been used most often following
tumor resection where hearing is lost. In some patients, sound recognition
can be improved. Many patients remain frustrated with standard hearing
aids. For patients with facial palsy, either caused by the tumor or following
treatment, a gold weight tarsorraphy can help with eye care. This device
is most often used in patients who have undergone a surgical resection
followed by a pronounced facial nerve deficit that is unlikely to improve
(ie. when anatomical continuity of the nerve is lost).
Physical/Speech
Therapy and Exercise
Physical therapy is important for patients who have ataxia or limb weakness
following acoustic tumor resection, or after placement of a shunt for
hydrocephalus. Patients should remain active following surgery to reduce
the chance for deep venous thromboses. In selected patients, balance retraining
may be of benefit.
Emerging
Therapies
Antineoplastic therapies such as chemotherapy or immunotherapy do not
play a role in this disorder. Whether novel anti-angiogenesis approaches
will be of value remains to be tested in preclinical and clinical trials.
A nude mouse human xenograft model has been useful to test the effects
of radiosurgery in the laboratory. This model may prove to be of value
for testing other emerging therapies as well.
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2001-06 The Department
of Neurosurgery, at the University
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